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4001: Leigh Syndrome Panel

Order this test

Test Code Test Name Turnaround Blood Sample Tissue Sample CPT Codes 2015 CPT Codes 2013
4001 Leigh Syndrome Panel 6 weeks $4,410.00 $4,510.00 81460, 81406, 81405 81479x2, 81406
mtDNA seq, POLG, Surf1

Selecting the Appropriate Sample Type

The ideal sample for this testing panel consists of a frozen muscle sample and a blood in a purple top (EDTA) tube (1-3 cc for children, 4-10 for adults). This panel can be performed on a blood sample if no other sample types are available.

  • Mitochondrial genome sequencing: Muscle or tissue samples are strongly preferred for the full mitochondrial genome sequencing portion of this testing panel, because post-mitotic tissues confer a higher detection rate for mitochondrial DNA mutations. Tissue Samples should be flash frozen, and shipped on dry ice by overnight courier. Please call the laboratory prior to sending any tissue sample.
  • POLG1 and Surf1: These are nuclear genes and testing can be performed on a blood sample. Blood samples should be sent to Mitomed by overnight courier at room temperature as soon as possible after being drawn. If the specimen can not be sent immediately, it should be stored refrigerated at 4 degrees C. The blood specimen must not be stored for more than 3 days at 4 degrees C.

About Leigh Syndrome

For more information about Leigh Syndrome, please visit the mtDNA associated Leigh and NARP profile at GeneTests.